Lethal West Nile Virus Infection Elicit Protective T Cell Immunity against Incorporate an Immundominant Peptide Single-Chain HLA-A2 MHC Trimers That
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Identification of Class I HLA T Cell Control Epitopes for West Nile Virus
The recent West Nile virus (WNV) outbreak in the United States underscores the importance of understanding human immune responses to this pathogen. Via the presentation of viral peptide ligands at the cell surface, class I HLA mediate the T cell recognition and killing of WNV infected cells. At this time, there are two key unknowns in regards to understanding protective T cell immunity: 1) the ...
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تاریخ انتشار 2010